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Decaethylene glycol

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Decaethylene glycol Basic information

Product Name:
Decaethylene glycol
Synonyms:
  • peg-10
  • DECAETHYLENE GLYCOL
  • 2,2'-[Oxybis[2,1-ethanediyloxy(2,1-ethanediyl)oxy(2,1-ethanediyl)oxy(2,1-ethanediyl)oxy]]bis(ethanol)
  • HO-PEG10-OH
  • 3,6,9,12,15,18,21,24,27-nonaoxanonacosane-1,29-diol
  • OH-PEG10-OH
  • 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • DecaethyleneGlycol>
CAS:
5579-66-8
MF:
C20H42O11
MW:
458.54
EINECS:
226-962-3
Product Categories:
  • Ethylene Glycols
  • Ethylene Glycols & Monofunctional Ethylene Glycols
  • peg
  • SiChem
Mol File:
5579-66-8.mol
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Decaethylene glycol Chemical Properties

Melting point:
28 °C
Boiling point:
280 °C / 7mmHg
Density 
1.115±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to lump to clear liquid
pka
14.06±0.10(Predicted)
color 
White or Colorless to Almost white or Almost colorless
InChI
InChI=1S/C20H42O11/c21-1-3-23-5-7-25-9-11-27-13-15-29-17-19-31-20-18-30-16-14-28-12-10-26-8-6-24-4-2-22/h21-22H,1-20H2
InChIKey
DTPCFIHYWYONMD-UHFFFAOYSA-N
SMILES
C(O)COCCOCCOCCOCCOCCOCCOCCOCCOCCO
EPA Substance Registry System
Decaethylene glycol (5579-66-8)
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Safety Information

HS Code 
2909498090
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Decaethylene glycol Usage And Synthesis

Description

PEG11 is a polymer consisting of 11 ethylene glycol subunits and two terminal hydroxyl groups. The hydroxyl groups can react to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility of the compound under aqueous environments. The water solubility properties of the PEG chain are enhanced with longer chains.

Uses

Decaethylene Glycol can be used as a corrosion inhibitor of aluminum surfaces.

Definition

ChEBI: Decaethylene glycol is a poly(ethylene glycol).

Application

Decaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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