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ACRIFLAVINE

Basic information Safety Supplier Related

ACRIFLAVINE Basic information

Product Name:
ACRIFLAVINE
Synonyms:
  • 2,8-DIAMINO-10-METHYLACRIDINIUM CHLORIDE
  • Acriflavine 10
  • Trypaflavine Neutral
  • GUANOSINE ULTRA PURE GRADE
  • 4-Acetamino phenol ( APAP )
  • Acriflavine 〔Trypaflavine〕
  • Acriflavine, 95%, mixture of 3,6-Diamino-10-methylacridinium Chloride and 3,6-Diaminoacridine
  • XANTHACRIDINE
CAS:
8048-52-0
MF:
C27H25ClN6
MW:
468.98
EINECS:
999-999-2
Product Categories:
  • marker
Mol File:
8048-52-0.mol
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ACRIFLAVINE Chemical Properties

Melting point:
179-181 °C
Boiling point:
612.69°C (rough estimate)
Density 
1.0933 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Store at -20°C
solubility 
H2O: soluble0.33g/mL (lit.)(lit.)
form 
Powder
color 
Deep orange to brownish-red
Merck 
14,123
CAS DataBase Reference
8048-52-0(CAS DataBase Reference)
EPA Substance Registry System
Xanthacridinum (8048-52-0)
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
22-37/38-41-50/53-20/21/22-50-36/37/38
Safety Statements 
26-39-60-61-36-37/39-29-36/37/39
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
RTECS 
AR9660000
HS Code 
38249064

MSDS

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ACRIFLAVINE Usage And Synthesis

Chemical Properties

Acriflavine hydrochloride is deep orange to brownish-red powder

Uses

Acriflavine is used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.

Uses

Fluorescent label for high molecular weight RNA

Safety Profile

Poison by subcutaneous route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. A topical antiseptic used in the treatment of gonorrhea. When heated to decomposition it emits very toxic fumes of NOx and Cl-. See also 3,6-DIAMINO-10 METHYLACRIDINIUM CHLORIDE.

Purification Methods

Treat acriflavin twice with freshly precipitated AgOH to remove proflavine, then recrystallise it from absolute methanol [Wen & Hsu J Phys Chem 66 1353 1962]. [Beilstein 22 III/IV 218.]

ACRIFLAVINESupplier

BIOISCO(Lianyungang, Jiangsu) Biotechnology Co., Ltd Gold
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18082049515
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2757382053@qq.com
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Sales-CN@TCIchemicals.com
Energy Chemical
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021-021-58432009 400-005-6266
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sales8178@energy-chemical.com