2-Trifluoromethylphenylboronic acid Chemical Properties

Melting point:

111-114 °C (lit.)

Boiling point:

274.5±50.0 °C(Predicted)

Density 

1.36±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

slightly sol. in Methanol

form 

powder to crystal

pka

8.11±0.58(Predicted)

color 

White to Almost white

BRN 

2974465

InChIKey

JNSBEPKGFVENFS-UHFFFAOYSA-N

CAS DataBase Reference

1423-27-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Trifluoromethylphenylboronic acid Usage And Synthesis

Chemical Properties

white to light beige crystalline powder

Uses

suzuki reaction

Uses

2-Trifluoromethylphenylboronic Acid is a reagent in the preparation of potent inhibitors of human uric acid transporter 1 (hURAT1).

Uses

2-(Trifluoromethyl)phenylboronic acid can be used as a reactant:

• In Suzuki-coupling reactions to prepare 2-trifluoromethyl aryl or heteroaryl derivatives.
• To synthesize 4-(2-trifluoromethyl)phenylpyrrolo[2,3-d]pyrimidine as a potential antagonist of corticotropin-releasing hormone.
• To prepare 2-nitro-6-(trifluoromethyl)phenylboronic acid by nitration reaction.

2-Trifluoromethylphenylboronic acid(1423-27-4)Related Product Information

• 5-Methyl-1H-benzotriazole
• (Trifluoromethyl)trimethylsilane
• 4-Bromobenzotrifluoride
• 2-(Trifluoromethyl)benzoic acid
• Citric acid
• Ethyl 2-(Chlorosulfonyl)acetate
• 3,5-Dimethylphenylboronic acid
• Folic acid
• 4-Aminobenzotrifluoride
• Phenylboronic acid
• 4-Tolylboronic acid
• 4-(Trifluoromethyl)benzaldehyde
• Benzotrifluoride
• Lithium trifluoromethanesulfonate
• Ascoric Acid
• 2-(TRIFLUOROMETHOXY)BENZALDEHYDE
• alpha,alpha,alpha-Trifluoro-o-cresol
• METHYL 2-(TRIFLUOROMETHOXY)BENZOATE