3,4-Difluorobenzonitrile Chemical Properties

Melting point:

52-54 °C (lit.)

Boiling point:

180 °C

Density 

1.2490 (estimate)

Flash point:

157 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to lump

color 

White to Light yellow

BRN 

2082224

InChIKey

BTBFCBQZFMQBNT-UHFFFAOYSA-N

CAS DataBase Reference

64248-62-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,T,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36/37-36/37/39

RIDADR 

UN 1325 4.1/PG 2

WGK Germany 

3

Hazard Note 

Toxic

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269090

MSDS

• Language:English Provider:3,4-Difluorobenzonitrile
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3,4-Difluorobenzonitrile Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

3,4-Difluorobenzonitrile has been used in the preparation of:

• fluorophenoxy herbicides
• fluorine substituted benzyl amides

Preparation

The preparation of 3,4-Difluorobenzonitrile is as follows:To the dry reactor was added 289.6 kg (1.843 kmoles) of 3,4-difluorobenzamide and 800 kg of dichloroethane solution, 241.2 kg (2.02 kmoles) of dichlorosulfoxide and catalyst DMF I.5 And the reaction was carried out at 50 ° C for 5 hours with stirring. After the reaction was complete, the reaction solution was poured into ice water with stirring and the mixture was separated to obtain a crude product having a qualitative content of 96% of 3,4-difluorobenzonitrile 259.1 kg (1.788 kmoles) in 97% yield. The crude product was distilled to give a qualitative content of 99% of 3,4,8-difluorobenzonitrile 248.6 kg (1.77 kmoles) and a distillation yield of 99%.

Application

3,4-Difluorobenzonitrile can be used as an intermediate of medicine, pesticide and liquid crystal material.

3,4-Difluorobenzonitrile(64248-62-0)Related Product Information

• 1,2-Difluorobenzene
• Florfenicol
• Transfluthrin
• 1,3-Difluorobenzene
• 2-Fluorobenzonitrile
• 2-Chloro-4,5-difluorobenzonitrile 98%,2-Chloro-4,5-difluorobenzonitrile98%,2-CHLORO-4,5-DIFLUOROBENZONITRILE
• 4-BROMO-2,6-DIFLUOROBENZONITRILE
• 3,5-Difluorobenzonitrile,99%,3,5-DIFLUOROBENZONITRILE,3,5-Difluorobenzonitrile98%
• 4-Amino-2,5-difluorobenzonitrile 98%,4-Amino-2,5-difluorobenzonitrile98%,4-Amino-2,5-difluorobenzonitrile,97+%,4-AMINO-2,5-DIFLUOROBENZONITRILE
• 3-CHLORO-2,6-DIFLUOROBENZONITRILE
• 2-CHLORO-3,6-DIFLUOROBENZONITRILE
• 2,6-DIFLUOROBENZONITRILE,2,6-Difluorobenzonitrile99%,2,6-DIFLUOROBENZONITRILE, 97+%
• 4-CHLORO-2,6-DIFLUOROBENZONITRILE
• 2,3-DIFLUOROBENZONITRILE,2,3-Difluorobenzonitrile98%,2,3-Difluorobenzonitrile 98%,2,3-Difluorobenzonitrile,99%
• 5-CHLORO-2,4-DIFLUOROBENZONITRILE
• 2,5-Difluorobenzonitrile,98%,2,5-DIFLUOROBENZONITRILE,2,5-Difluorobenzonitrile 98%
• 2-Cyano-3,4-difluorobenzonitrile
• 4-(bromomethyl)-2,3-difluorobenzonitrile