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3-DIETHYLAMINOPROPYL CHLORIDE

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3-DIETHYLAMINOPROPYL CHLORIDE Basic information

Product Name:
3-DIETHYLAMINOPROPYL CHLORIDE
Synonyms:
  • 3-chloropropyl(diethyl)amine
  • 3-CHLORO-1-DIETHYLAMINOPROPANE
  • N-(3-Chloropropyl)diethylamine, maleate salt
  • 3-Chloro-N,N-diethyl-1-propanamine
  • 3-chloro-N,N-diethyl-propan-1-amine
  • 3-chloro-N,N-diethylpropan-1-amine
  • 3-DIETHYLAMINOPROPYL CHLORIDE
  • 1-Chloro-3-diethylaminopropane
CAS:
104-77-8
MF:
C7H16ClN
MW:
149.66
EINECS:
203-235-9
Mol File:
104-77-8.mol
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3-DIETHYLAMINOPROPYL CHLORIDE Chemical Properties

Boiling point:
169-171℃
Density 
0.919±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
1.4541 (589.3 nm 20℃)
Flash point:
56.9±22.6℃
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
pka
10.10±0.25(Predicted)
color 
Clear Pale Yellow
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Safety Information

HS Code 
2921199990
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3-DIETHYLAMINOPROPYL CHLORIDE Usage And Synthesis

Chemical Properties

Crystalline, hygroscopic, melting point 223°C.

Uses

3-Chloro-N,N-diethylpropan-1-amine is used in the synthesis of propanamine antidepressants with similar efficacy to imipramine. Also used in the synthesis of inhibitors of fibroblast growth and endothelial growth based on substituted morpholines.

Synthesis Reference(s)

Journal of the American Chemical Society, 67, p. 1472, 1945 DOI: 10.1021/ja01225a018

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