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(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene

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(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene Basic information

Product Name:
(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene
Synonyms:
  • Progenin III(Prosapogenin A)
  • Progenin III
  • Prosapogenin A 【dioscin】
  • Prosapogenin A【Dioscorea tokoro】
  • Prosapogenin D'1
  • Polyphyllin E (= Prosapogenin A)
  • (25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene
  • [(25R)-Spirost-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
CAS:
19057-67-1
MF:
C39H62O12
MW:
722.9
Product Categories:
  • reagent
  • standard substance
Mol File:
19057-67-1.mol
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(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene Chemical Properties

Melting point:
212℃
Boiling point:
838.8±65.0 °C(Predicted)
Density 
1.34
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in methan
form 
powder
pka
12.85±0.70(Predicted)
color 
White
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(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene Usage And Synthesis

Description

Prosapogenin A is one of the important monomers of the extract of Chonglou, which has good anticancer effect. Compared with the currently commonly used antitumor drug oxaliplatin, it has stronger antitumor properties against colon cancer cells and has the potential to be an effective anticolon cancer drug.

Biological Activity

Prosapogenin A, a natural product in Veratrum, induces apoptosis in human cancer cells in vitro by inhibiting the STAT3 signaling pathway and glycolysis.

Source

Prosapogenin A comes from Huachonglou, lettuce flower, yam yam florets, yam yam

(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-eneSupplier

Chembest Research Laboratories Limited
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Chengdu Biopurify Phytochemicals Ltd.
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