4-Chloro-3-nitrobenzenesulfonamide Chemical Properties

Melting point:

25-35 °C

Boiling point:

175-176 °C

Density 

1.5966 (rough estimate)

refractive index 

1.6000 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

pka

9.28±0.60(Predicted)

form 

crystalline powder

color 

White to off white

Water Solubility 

224.8mg/L(15 ºC)

CAS DataBase Reference

97-09-6(CAS DataBase Reference)

EPA Substance Registry System

Benzenesulfonamide, 4-chloro-3-nitro- (97-09-6)

Safety Information

Hazard Codes 

Xi

Hazard Note 

Irritant

HS Code 

2935909099

Hazardous Substances Data

97-09-6(Hazardous Substances Data)

4-Chloro-3-nitrobenzenesulfonamide Usage And Synthesis

Chemical Properties

Light yellow to light brown crystalline powder

Uses

4-Chloro-3-nitrobenzenesulfonamide is used as a chemical intermediate for azo dyes.

Synthesis

Chlorosulphonic acid (450 mL) was slowly added to 2-chloronitrobenzene (100 g). The reaction mass was heated to 100°C and maintained at that temperat ure for 6 hours before cooling to ambient temperature and stirring for an additional 12 hours. The reaction mass was slowly poured into chilled aqueous ammonia (800 mL) and the reaction mixture was stirred for 3 hours at -10°C. The reaction mixture was then warmed to 23°C and stirred for 2 h ours. The reaction mixture was then filtered and the obtained solid was washed three times with water (200 mL x 3). The solid was dissolved in methanol (600 mL) at 60°C, charged with water (200 mL), and was stirred for 1 hour at 60°C. Again, the reaction mixture was charged with water (200 mL) and stirred for 1 hour at 60°C. Once again, the reaction mixtu re was charged with water (200 mL) and stirred for 1 hour. After cooling to room temperature and stirring for 1 hour, the reaction mixture was filtered, and the solid was washed with a 1 :1 mixture of methanol and water (100 mL). The solid was dried under vacuum at 60°C. Crystallization of the residue with toluen e gave the 4-Chloro-3-nitrobenzenesulfonamide(50 g).

4-Chloro-3-nitrobenzenesulfonamide(97-09-6)Related Product Information

• Sodium 3-nitrobenzenesulphonate
• 4-Nitrophenyl chloroformate
• Epichlorohydrin
• 1-Chloro-3-nitrobenzene
• 2-Nitrochlorobenzene
• 3,4-Difluoronitrobenzene
• Sulfanilamide
• 3-Nitrobenzaldehyde
• p-Toluenesulfonamide
• chloronitrobenzene
• Chloroacetic acid
• 4-Chloronitrobenzene
• Difluorochloromethane
• 1,3-Dinitrobenzene
• 3-NITRO-4-CHLORO BENZENE SULFONANILIDE
• 2-NITROCHLOROBENZENE-4-(N,N-DIMETHYL)-SULPHONAMIDE
• 2-NITROCHLOROBENZENE-4-SULFOMETHYL AMIDE
• 2-CHLORO-5-NITROBENZENESULFONAMIDE 98%,2-CHLORO-5-NITROBENZENESULFONAMIDE