(Bromoethynyl)triisopropylsilane Chemical Properties

Boiling point:

240.5±9.0 °C(Predicted)

Density 

1.073±0.06 g/cm3(Predicted)

refractive index 

1.49

storage temp. 

Storage temp. 2-8°C

form 

clear liquid

color 

Colorless to Red to Green

InChI

InChI=1S/C11H21BrSi/c1-9(2)13(8-7-12,10(3)4)11(5)6/h9-11H,1-6H3

InChIKey

HNNUBQWDWJNURV-UHFFFAOYSA-N

SMILES

[Si](C#CBr)(C(C)C)(C(C)C)C(C)C

CAS DataBase Reference

111409-79-1

Safety Information

HS Code 

2931900090

(Bromoethynyl)triisopropylsilane Usage And Synthesis

Description

(Bromoethynyl)triisopropylsilane is an important sterically hindered organosilicon protective agent, mainly used to protect various types of hydroxyl groups, especially in multifunctional hydroxyl compounds. It can be selectively protected and deprotected for the synthesis of nucleosides, nucleotides and sugar compounds.

Uses

(Bromoethynyl)triisopropylsilane could be used as an alkynylating reagen to synthesize the palladium-catalyzed primary amine-directed C(sp2)–H alkynylation of biaryl-2-amines[1].

References

[1] Jiang, Guangbin et al. “Palladium-catalyzed primary amine-directed regioselective mono- and di-alkynylation of biaryl-2-amines?.” Chemical Communications 14 (2018): 1746–1749.

(Bromoethynyl)triisopropylsilane(111409-79-1)Related Product Information

• triisopropylsilyl Methacrylate
• 4-METHYL-2-PENTYNE
• Chlorotrimethylsilane
• (TRIISOPROPYLSILYL)ACETYLENE
• Triisopropylsilane
• (Bromoethynyl)triisopropylsilane