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CYCLO(RGDFK(SAA))

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CYCLO(RGDFK(SAA)) Basic information

Product Name:
CYCLO(RGDFK(SAA))
Synonyms:
  • CYCLO(RGDFK(SAA))
  • GALACTO-RGD
  • Cyclo(-Arg-Gly-Asp-D-Phe-Lys(SAA))
  • c(RGDfK(SAA))
  • Galacto-RGD,Cyclo(RGDfK(SAA))
  • CYCLO(-ARG-GLY-ASP-D-PHE-LYS((2S,3R,4R,5R,6S)-6-AMINOMETHYL-3,4,5-TRIHYDROXY-TETRAHYDRO-PYRAN-2-CARBONYL))
  • c(RGDfK(galacto))
  • Cyclo[L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-N6-(7-amino-2,6-anhydro-7-deoxy-L-glycero-L-galacto-heptonoyl)-L-lysyl
CAS:
922175-70-0
MF:
C34H52N10O12
MW:
792.85
Mol File:
922175-70-0.mol
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CYCLO(RGDFK(SAA)) Chemical Properties

Density 
1.61±0.1 g/cm3(Predicted)
pka
4.01±0.10(Predicted)
Sequence
Cyclo(Arg-Gly-Asp-{d-Phe}-{Lys(SAA)})
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CYCLO(RGDFK(SAA)) Usage And Synthesis

Uses

Galacto-RGD is an RGD analogue that can be coupled with the radioactive isotope 18F and used as an integrin αβ selective tracer[1]. Galacto-RGD can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

References

[1] Ambros J Beer, et al. Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man. Clin Cancer Res. 2006 Jul 1;12(13):3942-9. DOI:10.1158/1078-0432.CCR-06-0266

CYCLO(RGDFK(SAA))Supplier

Alabiochem Tech.Co., Ltd.
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GL Biochem (Shanghai) Ltd
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