3-AMINO-5-CHLORO-N-CYCLOPROPYL-6-METHOXY-4-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
3-AMINO-5-CHLORO-N-CYCLOPROPYL-6-METHOXY-4-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Basic information
- Product Name:
- 3-AMINO-5-CHLORO-N-CYCLOPROPYL-6-METHOXY-4-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
- Synonyms:
-
- 3-AMINO-5-CHLORO-N-CYCLOPROPYL-6-METHOXY-4-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
- LY2033298
- Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-5-chloro-N-cyclopropyl-6-methoxy-4-methyl-
- CAS:
- 886047-13-8
- MF:
- C13H14ClN3O2S
- MW:
- 311.79
- Mol File:
- 886047-13-8.mol
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3-AMINO-5-CHLORO-N-CYCLOPROPYL-6-METHOXY-4-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Chemical Properties
- storage temp.
- -20°C
- solubility
- DMSO: >20mg/mL
- form
- solid
- color
- off-white to tan
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3-AMINO-5-CHLORO-N-CYCLOPROPYL-6-METHOXY-4-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE Usage And Synthesis
Uses
LY2033298 is an allosteric potentiator.
Biochem/physiol Actions
LY2033298 is a robust allosteric potentiator that is highly selective for the human M4 muscarinic acetylcholine receptor subtype. LY2033298 potentiates ACh-M4 binding, with no effect at M1/3/5 receptors. LY2033298 can also bind to the M ACh receptor, and mediate either positive or negative allosteric effects depending on the ligand used to probe receptor activity.
storage
Store at +4°C
3-AMINO-5-CHLORO-N-CYCLOPROPYL-6-METHOXY-4-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDESupplier
Sigma-Aldrich
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