Basic information Safety Supplier Related

Fmoc-D-homoArg(Et)2-OH·HCl

Basic information Safety Supplier Related

Fmoc-D-homoArg(Et)2-OH·HCl Basic information

Product Name:
Fmoc-D-homoArg(Et)2-OH·HCl
Synonyms:
  • Fmoc-D-homoArg(Et)2-OH·HCl
  • Fmoc-D-Har(Et)2-OH/Fmoc-D-HomoArg(Et)2-OH.HCl(symmetrical)
  • (2R)-6-[(E)-N',N''-diethylcarbamimidamido]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid hydrochloride
  • (2R)-6-[[amino(diethylamino)methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
  • Fmoc-d-homoarg(et)2-oh hydrochloride salt
  • Fmoc-D-homoArg(Et
  • Fmoc-D-homoArg(Et)2-OH (hydrochloride)
  • Fmoc-D-HomoArg(Et)2-0H.HC1
CAS:
2098497-24-4
MF:
C26H35ClN4O4
MW:
503.04
Mol File:
2098497-24-4.mol
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Fmoc-D-homoArg(Et)2-OH·HCl Usage And Synthesis

Uses

Fmoc-D-homoArg(Et)2-OH (hydrochloride) is a Fmoc-protected derivative of D-Homoarginine (HArg) that renders peptides and proteins resistant to proteolysis by trypsin. Fmoc-D-homoArg(Et)2-OH (hydrochloride) can be used as a cleavable ADC linker to synthesize antibody-drug conjugates (ADCs)[1].

References

[1] Zhu R, et al. An Efficient and Economical Method for the Preparation of Fmoc‐Argω, ω′(Boc) 2‐OH[J]. Chinese Journal of Chemistry, 2010, 28(8): 1508-1509.

Fmoc-D-homoArg(Et)2-OH·HClSupplier

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