Basic information Safety Supplier Related

Larotaxel

Basic information Safety Supplier Related

Larotaxel Basic information

Product Name:
Larotaxel
Synonyms:
  • Larotaxel
  • PNU 100940
  • XRP9881
  • Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (1S,2S,4S,7R,8aR,9aS,10aR,12aS,12bR)-7,12a-bis(acetyloxy)-1-(benzoyloxy)-1,3,4,7,8,9,9a,10,10a,12,12a,12b-dodecahydro-2-hydroxy-5,13,13-trimethyl-8-oxo-2,6-methano-2H-cyclodeca[3,4]cyclopropa[4,5]benz[1,2-b]oxet-4-yl ester, (...
  • Larotaxel USP/EP/BP
  • Paclitaxel Impurity 36(Larotaxel)
  • Larotaxel (XRP-9881)
  • (1S,2S,3R,4S,7R,9S,11R,13R,16S)-4,13-bis(acetyloxy)-16-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-15,18,18-trimethyl-12-oxo-6-oxapentacyclo[12.3.1.03,11.0?,?.0?,11]octadec-14-en-2-yl benzoate
CAS:
156294-36-9
MF:
C45H53NO14
MW:
831.9
Product Categories:
  • Aromatics
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
Mol File:
156294-36-9.mol
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Larotaxel Chemical Properties

Melting point:
170 - 174°C (dec.)
Boiling point:
889.3±65.0 °C(Predicted)
Density 
1.37
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
11.20±0.46(Predicted)
color 
White to Off-White
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Larotaxel Usage And Synthesis

Uses

Larotaxel (RPR 109881A) is a taxane analog with a broad spectrum of activity and different toxicity profile and with the possible advantages of surpassing some mechanisms of resistance and penetrating into the CNS.

LarotaxelSupplier

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