N-(4-biphenyl)-(9,9-dimethylfluoren-2--yl)Amine Chemical Properties

Melting point:

145.0 to 149.0 °C

Boiling point:

539.6±39.0 °C(Predicted)

Density 

1.136

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

0.90±0.40(Predicted)

color 

White to Off-White

InChI

InChI=1S/C27H23N/c1-27(2)25-11-7-6-10-23(25)24-17-16-22(18-26(24)27)28-21-14-12-20(13-15-21)19-8-4-3-5-9-19/h3-18,28H,1-2H3

InChIKey

QRMLAMCEPKEKHS-UHFFFAOYSA-N

SMILES

C1(C)(C)C2=C(C=CC=C2)C2=C1C=C(NC1=CC=C(C3=CC=CC=C3)C=C1)C=C2

CAS DataBase Reference

897671-69-1

Safety Information

HS Code 

2921490090

N-(4-biphenyl)-(9,9-dimethylfluoren-2--yl)Amine Usage And Synthesis

Chemical Properties

white powder

Uses

N-([1,1''-Biphenyl]-4-yl)-9,9-dimethyl-9H-fluoren-2-amine (cas# 897671-69-1) is a useful compound for preparing amine-containing organic compounds.

Synthesis

The general procedure for the synthesis of N-([1,1'-biphenyl]-4-yl)-9,9-dimethyl-9H-fluoren-2-amine from 9,9-dimethyl-2-bromofluorene and 4-amino biphenyl was as follows: in a reactor 50.0 g (330 mmol) of 4-amino biphenyl, 43.2 g (276 mmol) of 2-bromo-9,9-dimethyl-9H-fluorene, 1.2 g (5.6 mmol) palladium acetate, 6.4 g (11.02 mmol) phosphine ligand, and 126 g (386 mmol) cesium carbonate were dissolved in 1000 mL of toluene. The reaction mixture was stirred under reflux conditions for 24 hours. After completion of the reaction, it was cooled to room temperature, the reaction mixture was filtered and the filtrate was concentrated under reduced pressure. Purification by column chromatography afforded 57 g of the target product in 91% yield.

References

[1] Patent: KR2015/130797, 2015, A. Location in patent: Paragraph 0453-0458
[2] Patent: KR2015/114636, 2015, A. Location in patent: Paragraph 0546-0551
[3] Patent: CN107686484, 2018, A. Location in patent: Paragraph 0085-0088
[4] Patent: KR2016/78765, 2016, A. Location in patent: Paragraph 0187; 0190; 0195; 0196
[5] Patent: US2017/125688, 2017, A1. Location in patent: Paragraph 0314-0316

N-(4-biphenyl)-(9,9-dimethylfluoren-2--yl)Amine(897671-69-1)Related Product Information

• [2-(5-BROMO-THIOPHEN-2-YL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
• N-[1,1'-Biphenyl]-2-yl-9,9-dimethyl-9H-fluoren-2-amine
• N-[1,1'-Biphenyl]-4-yl-9,9-diphenyl-9H-fluoren-2-amine
• N-([1,1'-biphenyl]-3-yl)-9,9-diphenyl-9H-fluoren-amine