20,24-Dihydroxydammar-25-en-3-one Chemical Properties

Boiling point:

556.3±35.0 °C(Predicted)

Density 

1.027±0.06 g/cm3(Predicted)

pka

14.53±0.20(Predicted)

20,24-Dihydroxydammar-25-en-3-one Usage And Synthesis

Uses

20(S),24(S)-Dihydroxydammar-25-en-3-one (compound 19) is a kind of triterpene. 20(S),24(S)-Dihydroxydammar-25-en-3-one can be isolated from the floral spikes of Betula platyphylla var. 20(S),24(S)-Dihydroxydammar-25-en-3-one has cytotoxicity against Human Cancer Cell Lines[1].

Definition

ChEBI: 20S,24S-dihydroxydammer-25-en-3-one is a tetracyclic triterpenoid that is dammer-25-ene substituted by hydroxy groups at positions 20 and 24 and an oxo group at position 3 (the 24S-stereoisomer). It has been isolated from the stems of Aglaia abbreviata. It has a role as a plant metabolite. It is a tetracyclic triterpenoid, a cyclic terpene ketone and a diol. It derives from a hydride of a dammarane.

References

[1] Yoshiki Kashiwada, et al. Triterpenoids from the floral spikes of Betula platyphylla var. japonica and their reversing activity against multidrug-resistant cancer cells. J Nat Prod. 2007, 70, 4. DOI:10.1021/np060631s

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