Aristolactam FI Chemical Properties

Melting point:

>300 °C

Boiling point:

457.0±38.0 °C(Predicted)

Density 

1.441±0.06 g/cm3(Predicted)

pka

8.39±0.20(Predicted)

InChI

InChI=1S/C16H11NO3/c1-20-12-7-10-13-11(17-16(10)19)6-8-4-2-3-5-9(8)14(13)15(12)18/h2-7,18H,1H3,(H,17,19)

InChIKey

KBGNBPGXVKPRQI-UHFFFAOYSA-N

SMILES

N1C2=C3C(C(O)=C(OC)C=C3C1=O)=C1C=CC=CC1=C2

Aristolactam FI Usage And Synthesis

Uses

Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani[1].

Definition

ChEBI: Piperolactam A is an alkaloid.

IC 50

Leishmania

References

[1] Bhattacharya P, et al. In Vitro susceptibilities of wild and drug resistant Leishmania donovani amastigotes to piperolactam A loaded hydroxypropyl-β-cyclodextrin nanoparticles. Acta Trop. 2016 Jun;158:97-106. DOI:10.1016/j.actatropica.2016.02.017

Aristolactam FI(112501-42-5)Related Product Information

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• Artemether
• (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
• Hydroxyecdysone
• alpha-Cyperone
• MOSLOFLAVONE
• beta-Eudesmol
• 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
• beta-Sitosterol
• alpha-Terpineol
• ARISTOLACTAM-AII
• aristololactam BII