tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate Chemical Properties

Melting point:

45-49°C

Boiling point:

364.6±42.0 °C(Predicted)

Density 

1.168±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Solid

pka

13.69±0.20(Predicted)

color 

Pale Beige to Light Beige

Stability:

Hygroscopic

tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate Usage And Synthesis

Uses

(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester is an intermediate in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor.

tert-butyl (3R,5S)-6-chloro-3,5-dihydroxyhexanoate(154026-93-4)Related Product Information

• N-[(6R)-8-Fluoro-5,6-dihydro-4-(1-Methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-MethylMethanesulfonaMide
• 3-Oxo Rosuvastatin SodiuM Salt
• N-Desmethyl Rosuvastatin Lactone
• (4R-Cis)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester
• Rosuvastatin ethyl ester
• Rosuvastatin Impurity 91
• Rosuvastatin Related Compound 8
• Rosuvastatin Calcium Salt
• tert-Butyl 2-((4S,6S)-6-(chloromethyl(02,2-1,3-dioxan-4-yl)acetate
• NGABCYSYENPREI-RYUDHWBXSA-N
• 4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidine-5-carboxylic acid
• Rosuvastatin EP Impurity C
• Rosuvastatin EP impurity H
• Desfluoro Rosuvastatin Sodium Salt
• 5-PyriMidinecarboxylic acid, 4-(4-fluorophenyl)-1,2-dihydro-6-(1-Methylethyl)-2-oxo-, Methyl ester
• Phosphonium, [[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]me
• Ethyl propionylacetate
• Rosuvastatin Impurity 4