ChemicalBook > Product Catalog > Analytical Chemistry > Analysis reagents > Ion chromatography reagents > Silybin
Silybin
Silybin Basic information
- Product Name:
- Silybin
- Synonyms:
-
- Silybin A,B (Mixture)
- Silybin (Mixture of Diastereomers)
- 4H-1-Benzopyran-4-one, 2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-
- (2R,3R)-3,5,7-Trihydroxy-2-(3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one
- (2R,3R)-3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-o ne
- CAS:
- 802918-57-6
- MF:
- C25H22O10
- MW:
- 482.44
- EINECS:
- 806-403-5
- Product Categories:
-
- Aromatics
- Chiral Reagents
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Pharmaceuticals
- Mol File:
- 802918-57-6.mol
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Silybin Chemical Properties
- Melting point:
- 152-153°C
- Boiling point:
- 793.0±60.0 °C(Predicted)
- Density
- 1.527±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Acetone (Sparingly, Sonicated, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
- pka
- 7.39±0.60(Predicted)
- form
- Solid
- color
- Pale Yellow to Beige
- InChIKey
- SEBFKMXJBCUCAI-DBMPWETRSA-N
- SMILES
- [C@H]1(C2=CC=C3OC(CO)C(C4=CC=C(O)C(OC)=C4)OC3=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
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Silybin Usage And Synthesis
Chemical Properties
Beige Solid
Uses
Reference standard in the analysis of herbal medicinal products.
Uses
Hepatoprotectant. In nature, the flavonolignan Silybin occurs as a mixture of two diastereomers, Silybin A and Silybin B.
General Description
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
in vivo
Silybin (50, 100?mg/kg/day; given intragastrically for the last 4 weeks) significantly lowers both serum and hepatic lipid accumulation[2].
| Animal Model: | Male C57BL/6J mice (6-8 weeks old) with nonalcoholic fatty liver disease (NAFLD)[2] |
| Dosage: | 50, 100?mg/kg |
| Administration: | Given intragastrically; daily; for the last 4 weeks |
| Result: | Significantly lowered both serum and hepatic lipid accumulation. |
SilybinSupplier
J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Hubei kangen Pharmaceutical Chemical Co., Ltd
- Tel
- 153-15337215803 15337215803
- 3357312443@qq.com
Shanghai Haozhixiang Biotechnology Co., Ltd
- Tel
- 526763801 13301653310
- 526763801@qq.com