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H2N-PEG12-tBu

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H2N-PEG12-tBu Basic information

Product Name:
H2N-PEG12-tBu
Synonyms:
  • H2N-PEG12-tBu
  • AMINO-PEG12-PROPANOIC ACID T-BUTYL ESTER
  • Amino-PEG12-Boc
  • NH2-PEG12-CH2CH2COOtBu
  • tert-Butyl 1-amino-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oate
  • Amino-PEG12-t-Bu Ester
  • NH2-PEG12-tBu
  • PROTAC Linkers,inhibit,Amino PEG12 Boc,Inhibitor,Amino-PEG-12-Boc,AminoPEG12Boc
CAS:
1383814-00-3
MF:
C31H63NO14
MW:
673.83
Product Categories:
  • PEGylated Carboxylate
  • peg
Mol File:
1383814-00-3.mol
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H2N-PEG12-tBu Chemical Properties

Boiling point:
665.0±50.0 °C(Predicted)
Density 
1.080±0.06 g/cm3(Predicted)
storage temp. 
-20°C, protect from light
form 
Liquid
pka
8.74±0.10(Predicted)
color 
Colorless to light yellow
InChIKey
XRYCYKGEIYZQGE-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
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H2N-PEG12-tBu Usage And Synthesis

Uses

Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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