Basic information Safety Supplier Related

Maleimide-PEG4-NHS Ester

Basic information Safety Supplier Related

Maleimide-PEG4-NHS Ester Basic information

Product Name:
Maleimide-PEG4-NHS Ester
Synonyms:
  • alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol)
  • Mal-PEG4-NHS
  • N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide
  • O-[N-(3-MaleiMidopropionyl)aMinoethyl]-O′-[3-(N-succiniMidyloxy)-3-oxopropyl]triethylene glycol
  • O-[N-(3-Maleimidopropionyl)aminoethyl]-O'-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol >=90% (NMR)
  • Mal-amido-PEG4-NHS
  • 2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oate
  • MAL-DPEG4-NHS Ester
CAS:
756525-99-2
MF:
C22H31N3O11
MW:
513.49
EINECS:
201-258-5
Product Categories:
  • peg
Mol File:
756525-99-2.mol
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Maleimide-PEG4-NHS Ester Chemical Properties

Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO
form 
Solid
pka
15.01±0.46(Predicted)
color 
White to off-white
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Safety Information

WGK Germany 
3
HS Code 
2928009090
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Maleimide-PEG4-NHS Ester Usage And Synthesis

Description

Mal-amido-PEG4-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Maleimide-PEG4-NHS (CAS# 756525-99-2) is a cross-linking compound used in the lysosomal acid-triggered release of anticancer drugs.

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