1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester Chemical Properties

Boiling point:

327.3±15.0 °C(Predicted)

Density 

1.03±0.1 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

pka

1.98±0.10(Predicted)

form 

solid

color 

White to off-white

Safety Information

HS Code 

2933199090

1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester Usage And Synthesis

Synthesis

1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester could be synthesized through the reaction of 1-isopropyl-1H-pyrazole with 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. Tetrahydrofuran could used as an organic solvent. The crude product added n-hexane, heated to 40°C to dissolve the system, cooled to -20°C, stirred and crystallized, and filtered. Vacuum drying to obtain the target compound 1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester, with a yield of 77% and a purity of 99.3%.

1-Isopropyl-1H-pyrazole-5-boronic acid, pinacol ester(1282518-60-8)Related Product Information

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