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ent-17-Hydroxykaur-15-en-19-oic acid

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ent-17-Hydroxykaur-15-en-19-oic acid Basic information

Product Name:
ent-17-Hydroxykaur-15-en-19-oic acid
Synonyms:
  • ent-17-Hydroxykaur-15-en-19-oic acid
  • 17-Hydroxy-ent-kaur-15-en-19-oic acid
  • Kaur-15-en-18-oic acid, 17-hydroxy-, (4α)-
CAS:
35030-38-7
MF:
C20H30O3
MW:
318.46
Mol File:
35030-38-7.mol
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ent-17-Hydroxykaur-15-en-19-oic acid Chemical Properties

Melting point:
187-188 °C
Boiling point:
477.9±38.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
pka
4.68±0.60(Predicted)
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ent-17-Hydroxykaur-15-en-19-oic acid Usage And Synthesis

Uses

ent-17-Hydroxykaur-15-en-19-oic acid is a ent-kaurene diterpene that can be isolated from the leaves of Laetia thamnia L.. ent-17-Hydroxykaur-15-en-19-oic acid was cytotoxic to human prostate LNCaP2 cells with IC50 17.63 mg/mL[1].

References

[1] Pugazhendhi, D et al. “Effect of sulphation on the oestrogen agonist activity of the phytoestrogens genistein and daidzein in MCF-7 human breast cancer cells.” The Journal of endocrinology vol. 197,3 (2008): 503-15. doi:10.1677/JOE-07-0384 DOI:10.1677/JOE-07-0384

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