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3,4-(Methylenedioxy)cinnamic acid

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3,4-(Methylenedioxy)cinnamic acid Basic information

Product Name:
3,4-(Methylenedioxy)cinnamic acid
Synonyms:
  • 3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid
  • 3-(3,4-Methylene-dioxphenyl)acrylicacid
  • 3-(3,4-Methylenedioxyphenyl)propenoic acid
  • 3-(3,4-Methylenedioxyphenyl)propenoicacid
  • (2E)-3-(1,3-benzodioxol-5-yl)prop-2-enoic acid
  • 3,4-Methylenedioxybenzene-3-acrylic acid
  • Acetic acid, piperonylidene-
  • Cinnamic acid, 3,4-(methylenebis(oxy))-
CAS:
2373-80-0
MF:
C10H8O4
MW:
192.17
EINECS:
219-151-0
Product Categories:
  • Aromatic Cinnamic Acids, Esters and Derivatives
  • Cinnamic acid
  • C10
  • Carbonyl Compounds
  • Carboxylic Acids
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Organic Building Blocks
Mol File:
2373-80-0.mol
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3,4-(Methylenedioxy)cinnamic acid Chemical Properties

Melting point:
242-244 °C (dec.)(lit.)
Boiling point:
248.14°C (rough estimate)
Density 
1.0825 (rough estimate)
refractive index 
1.4440 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
very faint turbidity in Pyridine
form 
powder to crystal
pka
4.37±0.10(Predicted)
color 
White to Light yellow
BRN 
84599
InChIKey
QFQYZMGOKIROEC-DUXPYHPUSA-N
CAS DataBase Reference
2373-80-0(CAS DataBase Reference)
NIST Chemistry Reference
3,4-Methylenedioxycinnamic acid(2373-80-0)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
38-36/37/38
Safety Statements 
36-24/25-37-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29329990

MSDS

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3,4-(Methylenedioxy)cinnamic acid Usage And Synthesis

Chemical Properties

white to light yellow granular powder

Uses

3,4-(Methylenedioxy)cinnamic acid, predominantly trans is an inhibitor of the phenylpropanoid enzyme 4-hydroxycinnamoyl-CoA ligase.

Definition

ChEBI: Methylenedioxycinnamic acid is a hydroxycinnamic acid.

General Description

3,4-(Methylenedioxy)cinnamic acid is an inhibitor of the phenylpropanoid enzyme 4-hydroxycinnamoyl-CoA ligase. It undergoes electron transfer reaction with trichloromethylperoxyl radical and reaction has been studied by pulse radiolysis.

Purification Methods

Crystallise the acid from glacial AcOH, EtOH (m 247o) or aqueous EtOH (m 240-242o), and it has m 242o after sublimation. [Beilstein 19 H 278, 19 II 299, 19 III/IV 3548.]

3,4-(Methylenedioxy)cinnamic acid Preparation Products And Raw materials

Preparation Products

Raw materials

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