ZK118182 isopropyl ester
ZK118182 isopropyl ester Basic information
- Product Name:
- ZK118182 isopropyl ester
- Synonyms:
-
- ZK118182 isopropyl ester
- QLJUNFBXIBNQOL-LMJZMJOFSA-N
- ZK118182 isopropyl ester Exclusive
- propan-2-yl 2-[4-[5-chloro-2-(3-cyclohexyl-3-hydroxyprop-1-enyl)-3-hydroxycyclopentyl]but-2-enoxy]acetate
- Acetic acid, [[(2Z)-4-[(1R,2R,3R,5R)-5-chloro-2-[(1E,3S)-3-cyclohexyl-3-hydroxy-1-propenyl]-3-hydroxycyclopentyl]-2-butenyl]oxy]-, 1-methylethyl ester (9CI)
- ZK118182 isopropyl ester,ZK-118182 isopropyl ester
- CAS:
- 154927-31-8
- MF:
- C23H37ClO5
- MW:
- 428.99
- Mol File:
- 154927-31-8.mol
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ZK118182 isopropyl ester Chemical Properties
- Boiling point:
- 553.1±50.0 °C(Predicted)
- Density
- 1.14±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 3 mg/ml; DMSO: 2 mg/ml; Ethanol: 12.5 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
- pka
- 14.22±0.70(Predicted)
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ZK118182 isopropyl ester Usage And Synthesis
Description
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins (PGs) such as PGF2α and PGD2, have been shown to reduce IOP. ZK118182 is a PG analog that has potent DP-
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