2-Chloro-4-iodoaniline Chemical Properties

Melting point:

70-73 °C (lit.)

Boiling point:

281.7±25.0 °C(Predicted)

Density 

1.9011 (estimate)

storage temp. 

Refrigerated.

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

1.86±0.10(Predicted)

form 

powder to crystal

color 

Light yellow to Brown to Dark green

Sensitive 

Light Sensitive

BRN 

2081106

CAS DataBase Reference

42016-93-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

T,N,Xi,Xn

Risk Statements 

25-37/38-41-51/53-36/37/38-20/21/22

Safety Statements 

26-36/37-45-60-61-36/37/39

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

HazardClass 

6.1

PackingGroup 

III

HS Code 

29214200

MSDS

• Language:English Provider:2-Chloro-4-iodoaniline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chloro-4-iodoaniline Usage And Synthesis

Chemical Properties

grey to light orange crystalline powder

Uses

2-Chloro-4-iodoaniline is a chemical compound that has been synthesized for use as a reagent. It has been used to produce the drug cobimetinib, which is used in the treatment of cancer. 2-Chloro-4-iodoaniline can be prepared by reaction of magnesium with 2-chloroacetaldehyde and nitric acid. This reagent is also useful for preparing Grignard reagents. 2-Chloro-4-iodoaniline can be used to deaminate ketones, nitrates, and chlorides in high yield. 2,4,6-trichlorophenylalanine is an organic compound that contains all three functional groups: a chloride group, a ketone group, and an amino group. The chlorinated carbon atom of the chloride group makes it a good nucleophile and electrophile.

2-Chloro-4-iodoaniline(42016-93-3)Related Product Information

• Benzidine
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• 3-Chloroaniline
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• O-Tolidine
• o-Toluidine
• Aniline
• Chlorpropham
• 4-NITRO-2-SULFOANILINE
• 4-Chloroaniline
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• Difluorochloromethane
• PD184352 (CI-1040)
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• 2,4-DICHLOROANILINE