1-Bromoadamantane Chemical Properties

Melting point:

116-118 °C (lit.)

Boiling point:

248.79°C (rough estimate)

Density 

1.2686 (rough estimate)

refractive index 

1.6411 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Powder

color 

White to yellow

Water Solubility 

It is soluble in organic solvents and insoluble in water.

Sensitive 

Moisture Sensitive

BRN 

1098857

InChI

InChI=1S/C10H15Br/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6H2

InChIKey

VQHPRVYDKRESCL-UHFFFAOYSA-N

SMILES

C12(Br)CC3CC(CC(C3)C1)C2

CAS DataBase Reference

768-90-1(CAS DataBase Reference)

NIST Chemistry Reference

1-Bromoadamantane(768-90-1)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

F 

8-10-23

HS Code 

29035990

MSDS

• Language:English Provider:1-Bromotricyclo[3.3.1.1(3,7)]decane
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1-Bromoadamantane Usage And Synthesis

Chemical Properties

WHITE TO ALMOST WHITE CRYSTALS OR CRYST. POWDER

Uses

use: Amantadine, Rimantadine, Somantadine, Tromantadine

Uses

1-Bromoadamantane is an important intermediate, used in synthesizing medicines and new materials etc.

Uses

1-Bromoadamantane shows some anti-viral activity due to the adamantane structure. In addition it shows anti-microbial activity and cytotoxic application.

Application

1-Bromoadamantane was used in the synthesis of a new organic–organic nanoscale composite thin-film dielectric.
1-Bromoadamantane forms inclusion complexes with α-, β-, and γ-cyclodextrins. It causes the alkylation of Co(II) complexes of β-diketones.

Synthesis Reference(s)

The Journal of Organic Chemistry, 45, p. 5239, 1980 DOI: 10.1021/jo01314a003

General Description

1-Bromoadamantane forms inclusion complexes with α-, β-, and γ-cyclodextrins. It causes the alkylation of Co(II) complexes of β-diketones.

Purification Methods

If coloured, dissolve it in CCl4, wash with H2O, treat with charcoal, dry (CaCl2), filter and evaporate to dryness. Dissolve the residue in a small volume of MeOH and cool in a CO2/trichloroethylene bath and collect the crystals. Sublime it at 90-100o/water pump vacuum. [Stetter et al. Chem Ber 92 1629 1959, Schleyer & Nicholas J Am Chem Soc 83 2700 1961, Beilstein 5 III 469.]

1-Bromoadamantane(768-90-1)Related Product Information

• Adamantane
• Altrenogest
• Amantadine
• Decane
• 1,3-Dimethyl-5-bromoadamantane
• 1,4-Dibromoadamantane
• Bromocyclohexane
• CYCLOOCTYL BROMIDE
• 1-BROMO-3-METHYLCYCLOHEXANE
• 2-BROMO-6-METHYLHEPTANE
• 2-CYCLOHEXYLETHYL BROMIDE
• 3-BROMOOCTANE
• 1-BROMO-5-METHYLHEXANE
• Bromoadamantane,2-Bromoadamantane,98%,2-BROMOADAMANTANE
• 3-BROMOADAMANTANE-1-CARBOXYLIC ACID
• 1-Adamantanol
• 1,3-Dibromoadamantane
• 2-Bromoheptane