5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]- Basic information
- Product Name:
- 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
- Synonyms:
-
- 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
- (S)-4-(3-chloro-4-MethoxybenzylaMino)-5-carboxy-2-(2-hydroxyMethyl-1-pyrrolidinyl)pyriMidine
- 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-5-pyrimidinecarboxylic acid
- (S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)pyriMidine-5-carboxylic acid
- 4-(3-chloro-4-methoxybenzylamino) -2-((S)-2-(hydroxymethyl) pyrrolidin-1-yl)pyrimidine-5- carboxylic acid
- (S)-4-(3-Chloro-4-Methoxybenzyl)Amino)-2-(2-(Hydroxymethyl)Pyrolidin-1-Yl)Pyrimidine-5-Carboxylic Acid
- 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid
- 5-PYRIMIDINECARBOXYLIC ACID, 4-[[(3-CHLORO-4-METHOXYPHENYL)METHYL]AMINO]-2-[(2S)-2-(HYDROXYMETHYL)-
- CAS:
- 330785-84-7
- MF:
- C18H21ClN4O4
- MW:
- 392.84
- EINECS:
- 807-887-0
- Mol File:
- 330785-84-7.mol
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5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]- Chemical Properties
- Melting point:
- >176oC (dec.)
- Boiling point:
- 647.6±65.0 °C(Predicted)
- Density
- 1.415±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 1.80±0.36(Predicted)
- color
- White
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5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]- Usage And Synthesis
Uses
(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic Acid is used in the preparation of an Avanafil (A794670) intermediate. Avanafil is a phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.
5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-Supplier
ChemFuture PharmaTech (Jiangsu) Ltd
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- 5108538618
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
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- +86-21-54098501
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Emei shan Hongsheng Pharmaceutical Co., LTD
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- 0833-6186272、6186278、6170066 18990613291
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Hubei XinyuanShun Chemical Co., Ltd.
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- 13971561712, 13995564702, 027-50664929
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Taizhou Tongxin Bio-Tech Co., Ltd
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- 0523-18601685-898 18652728585
- sales@allyrise.com
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5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-(330785-84-7)Related Product Information
- Avanafil Impurity 24
- Avanafil Impurity 19
- Avanafil Impurity 9
- Avanafil Impurity 26
- Avanafil Impurity 16
- Avanafil Impurity 10
- 4-(4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylthiopyriMidine
- Avanafil Impurity 25
- Avanafil Impurity 20
- Avanafil iMpurity 2
- Avanafil Impurity 23
- 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid
- Avanafil iMpurity 5
- 1364671-52-2
- Avanafil-13CD3
- Avanafil Impurity 11
- Avanafil iMpurity 3
- Avanafil Impurity 21