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Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib

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Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Basic information

Product Name:
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib
Synonyms:
  • Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib
  • 5-Thiazolecarboxamide, N-[2-chloro-6-(hydroxymethyl)phenyl]-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-
  • Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib/N-[2-Chloro-6-(hydroxymethyl)phenyl]-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide
CAS:
910297-71-1
MF:
C16H13Cl2N5O2S
MW:
410.28
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Tyrosine Kinase Inhibitors
Mol File:
910297-71-1.mol
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Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Chemical Properties

Melting point:
237-240°C
Density 
1.593±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
10.69±0.70(Predicted)
form 
Solid
color 
Pale Beige
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Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib Usage And Synthesis

Uses

Intermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases. It is a COVID19-related research product.

Uses

Intermediate in the preparation of Dasatinib metabolite, Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib is used in the treatment of cancers and immune diseases.

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