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INDOLE-3-GLYOXYLYL CHLORIDE

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INDOLE-3-GLYOXYLYL CHLORIDE Basic information

Product Name:
INDOLE-3-GLYOXYLYL CHLORIDE
Synonyms:
  • 3-INDOLYLGLYOXALYL CHLORIDE
  • 3-INDOLYL-GLYOXYL CHLORIDE
  • 3-INDOLEGLYOXYLYL CHLORIDE
  • ALPHA-OXO-INDOLE-3-ACETYL CHLORIDE
  • INDOLE-3-GLYOXYLOYL CHLORIDE
  • INDOLE-3-GLYOXYLYL CHLORIDE
  • (2-(3-INDOLYL)-2-OXOACETYL) CHLORIDE
  • alpha-Oxoindoleacetyl chloride
CAS:
22980-09-2
MF:
C10H6ClNO2
MW:
207.61
EINECS:
245-362-2
Product Categories:
  • Aromtatics, Heterocycles, Indole Derivatives, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Building Blocks
  • Aromtatics
  • C10
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • Heterocycles
  • Impurities
  • Indole Derivatives
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocyclic Compounds
Mol File:
22980-09-2.mol
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INDOLE-3-GLYOXYLYL CHLORIDE Chemical Properties

Melting point:
138 °C (dec.) (lit.)
Boiling point:
413.9±37.0 °C(Predicted)
Density 
1.463±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
14.29±0.30(Predicted)
Sensitive 
Moisture Sensitive
BRN 
147693
CAS DataBase Reference
22980-09-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-27-36/37/39-45
RIDADR 
UN 1759 8/PG 2
WGK Germany 
3
HazardClass 
8
PackingGroup 
II

MSDS

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INDOLE-3-GLYOXYLYL CHLORIDE Usage And Synthesis

Uses

• ;Reactant for preparation of dual IGF-1R/SRC inhibitors1• ;Reactant for preparation of indolylglyoxylamides as a new class of antileishmanial agents2• ;Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents3• ;Reactant for diastereoselective synthesis of heptacyclic core of dragmacidin E4• ;Reactant for preparation of benzoylmethylpyrrolopyridinylethanedione as HIV-1 inhibitor5• ;Reactant for preparation of fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D16

Uses

  • Reactant for preparation of dual IGF-1R/SRC inhibitors
  • Reactant for preparation of indolylglyoxylamides as a new class of antileishmanial agents
  • Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents
  • Reactant for diastereoselective synthesis of heptacyclic core of dragmacidin E
  • Reactant for preparation of benzoylmethylpyrrolopyridinylethanedione as HIV-1 inhibitor
  • Reactant for preparation of fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1

Uses

INDOLE-3-GLYOXYLYL CHLORIDE is an indole derivative used in the preparation of reagents for chemiluminescent enzyme immunoassay. It is an impurity in the manufacture of tryptamines and related compounds.

INDOLE-3-GLYOXYLYL CHLORIDESupplier

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