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4-Difluoromethoxy-3-hydroxybenzaldehyde

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4-Difluoromethoxy-3-hydroxybenzaldehyde Basic information

Product Name:
4-Difluoromethoxy-3-hydroxybenzaldehyde
Synonyms:
  • 2-(Difluoromethoxy)-5-formylphenol, alpha,alpha-Difluoro-4-formyl-2-hydroxyanisole
  • Benzaldehyde,4-(difluoroMethoxy)-3-hydroxy-
  • Roflumilast impurity 19
  • 3-Hydroxy-4-diflouromethylbenzaldehyde
  • 4-(Difluoromethoxy)-3-hydroxybenzaldehyde 97%
  • 4-(Difluoromethoxy)-3-hydroxybenzaldehyde97%
  • 3-hydroxy-4-difluoroMethoxy benzaldehyde
  • 4-DIFLUOROMETHOXY-3-HYDROXYBENZALDEHYDE
CAS:
151103-08-1
MF:
C8H6F2O3
MW:
188.13
EINECS:
687-745-0
Product Categories:
  • Roflumilast interemdiate
  • Aromatics
  • Aldehydes
  • Phenyls & Phenyl-Het
  • Phenyls & Phenyl-Het
  • Intermediates
  • Intermediate
Mol File:
151103-08-1.mol
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4-Difluoromethoxy-3-hydroxybenzaldehyde Chemical Properties

Melting point:
85-90°C
Boiling point:
280.6±35.0 °C(Predicted)
Density 
1.395±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
7.85±0.35(Predicted)
color 
White
InChI
InChI=1S/C8H6F2O3/c9-8(10)13-7-2-1-5(4-11)3-6(7)12/h1-4,8,12H
InChIKey
ZLIKNROJGXXNJG-UHFFFAOYSA-N
SMILES
C(=O)C1=CC=C(OC(F)F)C(O)=C1
CAS DataBase Reference
151103-08-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-51-22
Safety Statements 
26-36/37/39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2913000090
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4-Difluoromethoxy-3-hydroxybenzaldehyde Usage And Synthesis

Chemical Properties

4-Difluoromethoxy-3-hydroxybenzaldehyde is white powder

Uses

4-Difluoromethoxy-3-hydroxybenzaldehyde is a phenyl alkyl ketone derivative used in the preparation of phosphodiesterase-4 (PDE4) inhibitors.

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