ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > PI3K / Akt / mTOR > Akt inhibitors > GSK-2110183C
GSK-2110183C
GSK-2110183C Basic information
- Product Name:
- GSK-2110183C
- Synonyms:
-
- Afuresertib(GSK2110183C)
- Afuresertib
- GSK 2110183C
- GSK2110183C
- GSK-2110183C
- N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
- Afuresertib, GSK-2110183, GSK-2110183B
- Delitinib
- CAS:
- 1047644-62-1
- MF:
- C18H17Cl2FN4OS
- MW:
- 427.32
- EINECS:
- 1592732-453-0
- Product Categories:
-
- Inhibitors
- Mol File:
- 1047644-62-1.mol
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GSK-2110183C Chemical Properties
- Boiling point:
- 535.1±50.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C, protect from light, stored under nitrogen
- solubility
- DMSO:62.5(Max Conc. mg/mL);146.26(Max Conc. mM)
Ethanol:85.0(Max Conc. mg/mL);198.91(Max Conc. mM) - pka
- 13.03±0.46(Predicted)
- form
- Powder
- color
- White to off-white
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GSK-2110183C Usage And Synthesis
Uses
Afuresertib is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib in preclinical models of multiple myeloma.
Definition
ChEBI: N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methyl-3-pyrazolyl)-2-thiophenecarboxamide is a member of amphetamines.
GSK-2110183CSupplier
SuZhou GoodChemTech Co., Ltd Gold
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- 18136139868
- jinlun@goodchemtech.cn
Shanghai Boyle Chemical Co., Ltd.
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- sales@boylechem.com
Chembest Research Laboratories Limited
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- +86-21-20908456
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Beijing Yisiyan Technology Research Center
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- 010-56645598 13366904824
- bjkaida@163.com
Haoyuan Chemexpress Co., Ltd.
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- 021-58950125
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