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GSK-2110183C

Basic information Safety Supplier Related

GSK-2110183C Basic information

Product Name:
GSK-2110183C
Synonyms:
  • Afuresertib(GSK2110183C)
  • Afuresertib
  • GSK 2110183C
  • GSK2110183C
  • GSK-2110183C
  • N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
  • Afuresertib, GSK-2110183, GSK-2110183B
  • Delitinib
CAS:
1047644-62-1
MF:
C18H17Cl2FN4OS
MW:
427.32
EINECS:
1592732-453-0
Product Categories:
  • Inhibitors
Mol File:
1047644-62-1.mol
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GSK-2110183C Chemical Properties

Boiling point:
535.1±50.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C, protect from light, stored under nitrogen
solubility 
DMSO:62.5(Max Conc. mg/mL);146.26(Max Conc. mM)
Ethanol:85.0(Max Conc. mg/mL);198.91(Max Conc. mM)
pka
13.03±0.46(Predicted)
form 
Powder
color 
White to off-white
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GSK-2110183C Usage And Synthesis

Uses

Afuresertib is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib in preclinical models of multiple myeloma.

Definition

ChEBI: N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methyl-3-pyrazolyl)-2-thiophenecarboxamide is a member of amphetamines.

GSK-2110183CSupplier

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