Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)

Basic information Safety Supplier Related

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) Basic information

Product Name:
CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)
Synonyms:
  • (S)-tert-butyl 2,6-dimethyl-3-oxohept-1-en-4-ylcarbamate
  • Carbamic acid, N-[(1S,2R)-2-hydroxy-3-methyl-1-(2-methylpropyl)-3-buten-1-yl]-, 1,1-dimethylethyl ester
  • tert-butyl(S)-(2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate
  • Carbamic acid, [(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-butenyl]-, 1,1-dimethylethyl ester
  • tert-butyl-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxobut-3-en-1-yl]carbamate
  • PR171 Intermediate
  • CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)
  • (S)-4-(tert-Butoxycarbonylamino)-2,6-dimethyl-1-hepten-3-one
CAS:
247068-81-1
MF:
C14H25NO3
MW:
255.35
Mol File:
247068-81-1.mol
More
Less

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) Chemical Properties

Boiling point:
350.4±25.0 °C(Predicted)
Density 
0.964±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
11.05±0.46(Predicted)
More
Less

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI) Usage And Synthesis

Uses

tert-Butyl ((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate is an intermediate in the synthesis of (S)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt which is an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.

CarbaMic acid, [(1S)-3-Methyl-1-(2-Methylpropyl)-2-oxo-3-butenyl]-, 1,1-diMethylethyl ester (9CI)Supplier

Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd. Gold
Tel
15981924004
Email
wangyangguang@trizpharma.cn
Baiyi chemical (lianyungang) co. LTD Gold
Tel
18552648286
Email
dajingsheng@126.com
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18934348241
Email
sales4.gd@hwrkchemical.com
Energy Chemical
Tel
021-021-58432009 400-005-6266
Email
sales8178@energy-chemical.com
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Email
chenyj@titansci.com