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Grela 2nd Generation

Basic information Reaction Safety Supplier Related

Grela 2nd Generation Basic information

Product Name:
Grela 2nd Generation
Synonyms:
  • RutheniuM, [1,3-bis(2,4,6-triMethylphenyl)-2-iMidazolidinylidene]dichloro[[2-(1-Methylethoxy-κO)-5-nitrophenyl]Methylene-κC]-, (SP-5-41)-
  • [1,3-bis (2,4,6-trimethylphenyl) -2- imidazolidinylidene] (2-isopropoxy-5-nitrophenyl methylene) ruthenium dichloride
  • nitro-Grela
  • (SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-kO)-5-nitrophenyl]Methylene-kC]-ruthenium
  • Grela nitro-Grela
  • 1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(5-nitro-2-propan-2-yloxyphenyl)methylidene]ruthenium
  • Grela's catalyst
  • Grela 2
CAS:
502964-52-5
MF:
C31H36Cl2N3O3Ru
MW:
670.62
Mol File:
502964-52-5.mol
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Grela 2nd Generation Chemical Properties

Melting point:
>300 °C
storage temp. 
2-8°C
form 
Powder
color 
green
CAS DataBase Reference
502964-52-5
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Safety Information

HS Code 
2931.90.6000
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Grela 2nd Generation Usage And Synthesis

Reaction

  1. This catalyst is used for an efficient synthesis of HCV Protease Inhibitor, BILN 2061.
  2. The nitro-Grela catalyst is a stable olefin metathesis initiator active in various ring-closing, cross, and enyne metathesis reactions. Its efficiency has been proven in numerous total syntheses of natural and biologically active compounds, and in material science.

Uses

nitro-Grela is a universal catalyst which provides good results in a wide spectrum of olefin metathesis transformations. The catalyst provides high efficiency in cross metathesis (CM) reactions between type 1 olefins and an electron deficient partner. The catalyst is very good for CM of disubstituted internal olefins.

Grela 2nd GenerationSupplier

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