2-THIOADENOSINE Chemical Properties

Melting point:

>178°C (dec.)

Boiling point:

544.5±60.0 °C(Predicted)

Density 

2.18±0.1 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

solubility 

Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)

form 

Solid

pka

8.37±0.40(Predicted)

color 

Pale Yellow to Yellow

CAS DataBase Reference

43157-50-2

Safety Information

HS Code 

2934999090

2-THIOADENOSINE Usage And Synthesis

Description

2-Thioadenosine is a pharmaceutical intermediate compound used in the preparation of cangrelor, a P2Y12 platelet receptor antagonist used to prevent or reduce the risk of thrombosis during stenting procedures. In biology, it regulates the synthesis and degradation of important biomolecules such as DNA, RNA and proteins. It also regulates cell signalling pathways, including those involved in cell growth, proliferation and apoptosis. In addition, it plays a role in maintaining cellular redox balance and regulating oxidative stress.

Uses

2-Thioadenosine has application for developing platelet aggregation inhibitors.

Application

Intermediate in the synthesis of cangrelor

2-THIOADENOSINE(43157-50-2)Related Product Information

• S-Adenosyl-L-methionine
• Adenosine 5'-monophosphate
• ADENOSINE5'-MONOPHOSPHATESODIUMSALT
• ADENOSINE 5'-DIPHOSPHATE MONOPOTASSIUM SALT
• ATP disodium salt
• ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL&
• Adenine
• Adenosine-5'-diphosphate disodium salt
• 2-THIOADENOSINE
• 6-AMINO-2-MERCAPTOPURINE