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Loratadine 2-Chloro IMpurity

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Loratadine 2-Chloro IMpurity Basic information

Product Name:
Loratadine 2-Chloro IMpurity
Synonyms:
  • Loratadine 2-Chloro IMpurity
  • Loratadine Impurity 26
  • Ethyl 4-(2,8-Dichloro-5,6-dihydro-1
  • 1-Piperidinecarboxylic acid, 4-(2,8-dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester
  • ethyl 4-(2,8-dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
  • Loratadine EP Impurity 18
CAS:
165739-64-0
MF:
C22H22Cl2N2O2
MW:
417.33
Mol File:
165739-64-0.mol
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Loratadine 2-Chloro IMpurity Chemical Properties

Boiling point:
554.6±50.0 °C(Predicted)
Density 
1.322±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
-0.33±0.20(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
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Loratadine 2-Chloro IMpurity Usage And Synthesis

Uses

2-Chloro Loratadine is an impurity of Loratadine (L469575), a nonsedating-type histamine H1-Receptor blocker.

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