Sitagliptin DeaMino IMpurity 1 Chemical Properties

Boiling point:

517.5±60.0 °C(Predicted)

Density 

1.52±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol

pka

-0.06±0.20(Predicted)

form 

Solid

color 

Colourless to Pale Yellow Gel to Waxy

Stability:

Hygroscopic

Sitagliptin DeaMino IMpurity 1 Usage And Synthesis

Uses

3-Desamino-2,3-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin DeaMino IMpurity 1(1253056-18-6)Related Product Information

• BOC-(S)-3-AMINO-4-(2,4,5-TRIFLUORO-PHENYL)-BUTYRIC ACID
• Sitagliptin
• Sitagliptin Defuoro IMpurity 3
• tert-Butyl ((R)-4-Oxo-4-(((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)amino)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate
• 1,2,4-Triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione, 6,7,10,11-tetrahydro-3-(trifluoromethyl)-10-[(2,4,5-trifluorophenyl)methyl]-
• Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
• 1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)-
• (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
• Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate
• Sitagliptin IMpurity
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
• Sitagliptin Impurity 34
• Sitagliptin N-Phoshate IMpurity
• Sitagliptin impurity H HCl
• Sitagliptin Impurity 31
• Sitagliptin phosphate
• Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)-
• (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid