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9,11-Dehydro-17α-cyanoMethyl Estradiol

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9,11-Dehydro-17α-cyanoMethyl Estradiol Basic information

Product Name:
9,11-Dehydro-17α-cyanoMethyl Estradiol
Synonyms:
  • 9,11-Dehydro-17α-cyanoMethyl Estradiol
  • 17α-Cyanomethylestra-1,3,5(10),9(11)-tetraen-3,17β-diol
  • 19-Norpregna-1,3,5(10),9(11)-tetraene-21-nitrile, 3,17-dihydroxy-, (17α)- (9CI)
  • Dienogest Impurity 3 (Dienogest EP Impurity G)
  • 17a-Cyanomethylestra-1,3,5(10),9(11)-tetraene-3,17b-diol
  • [(17β)-3,17-Dihydroxyestra-1,3,5(10),9(11)-tetraen-17-yl]acetonitrile
  • 9,11-Dehydro-17α-cyanoMethyl Estradiol
  • (17α-Cyanomethylestra-1,3,5(10),9(11)-tetraen-3,17β-diol)
CAS:
86153-38-0
MF:
C20H23NO2
MW:
309.41
Product Categories:
  • Steroids, Pharmaceuticals, Intermediates & Fine Chemicals, Metabolites & Impurities, Drug Analogues
Mol File:
86153-38-0.mol
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9,11-Dehydro-17α-cyanoMethyl Estradiol Chemical Properties

Melting point:
228 - 233°C
Boiling point:
551.2±50.0 °C(Predicted)
Density 
1.25±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
10.37±0.60(Predicted)
form 
Solid
color 
White to Off-White
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9,11-Dehydro-17α-cyanoMethyl Estradiol Usage And Synthesis

Uses

9,11-Dehydro-17α-cyanomethyl Estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.

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