c-di-AMP Chemical Properties

Boiling point:

1096.7±75.0 °C(Predicted)

Density 

2.52±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Soluble in DMSO

form 

powder

pka

0.96±0.70(Predicted)

color 

white to beige

c-di-AMP Usage And Synthesis

Uses

Cyclic di-AMP (c-di-AMP) is a second messenger produced by bacteria. It impacts bacterial cell growth, cell wall homeostasis, pathogenicity, and other cellular functions.

Definition

ChEBI: Cyclic di-AMP is a cyclic purine dinucleotide that is the 3',5'-cyclic dimer of AMP. It has a role as a Mycoplasma genitalium metabolite. It is a cyclic purine dinucleotide and an adenyl ribonucleotide. It is a conjugate acid of a cyclic di-AMP(2-).

Biochem/physiol Actions

c-di-AMP is a bacterial secondary messenger. c-di-AMP acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.

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