DSPE-PEG-NH2
DSPE-PEG-NH2 Basic information
- Product Name:
- DSPE-PEG-NH2
- Synonyms:
-
- 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[aMino(polyethylene glycol)-2000] (aMMoniuM salt)
- DSPE-PEG-2K-Amine
- DSPE-PEG(2000) Amine
- 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-[AMINO(POLYETHYLENE GLYCOL)-2000] (AMMONIUM SALT);DSPE-PEG(2000) AMINE
- DSPE-PEG2000-NH2
- DSPE-PEG-NH2
- DSPE-PEG-NH2 ISO 9001：2015 REACH
- Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-(2-aminoethoxy)-, ammonium salt (1:1)
- CAS:
- 474922-26-4
- MF:
- (C2H4O)nC44H87N2O10P.H3N
- MW:
- 0
- Product Categories:
-
- peg
- Mol File:
- 474922-26-4.mol
DSPE-PEG-NH2 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMF: 11 mg/ml,Ethanol: 20 mg/ml
- form
- Solid
- color
- White to off-white
- InChIKey
- AXHRCGLQEUQOIS-UHFFFAOYSA-N
- SMILES
- C(COC(=O)CCCCCCCCCCCCCCCCC)(OC(=O)CCCCCCCCCCCCCCCCC)COP(O)(=O)OCCNC(=O)O{-}CC{+n}OCCN.N
DSPE-PEG-NH2 Usage And Synthesis
Description
DSPE-PEG-Amine, MW 2,000 is a PEG polymer containing DSPE and amine end groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG increases the water solubility of the overall compound allowing for the delivery of the drug. The amine group can react with activated NHS ester to form a stable amide bond.
Uses
DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.
References
[1] Nagata H, et al. Preparation and Catalytic Properties of Carbonic Anhydrase Conjugated to Liposomes through a Bis-Aryl Hydrazone Bond. ACS Omega. 2023 May 16;8(21):18637-18652. DOI:10.1021/acsomega.3c00551
DSPE-PEG-NH2Supplier
- Tel
- 021-59555769 13524932310
- 1405894150@qq.com
- Tel
- 400-400-6966-012-012 17778955912
- 2957605606@qq.com
- Tel
- 021-58876118 15692161719
- avt013@avt-cn.com
- Tel
- 020-020-37239396 18922492046
- weihuasw@foxmail.com
- Tel
- 023-62795528 18896157519
- 18896157519@139.com
DSPE-PEG-NH2(474922-26-4)Related Product Information
- 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
- DSPE-PEG2000-SH
- 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT)
- DPPE-MPEG 5000
- DSPE-PEG2000-FITC
- DSPE-PEG-Mal
- N-PALMITOYL-D-SPHINGOMYELIN
- L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL
- 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
- 1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
- MPEG-2000-DSPE
- 1-OLEOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE
- 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[PDP(polyethylene glycol)-2000] (aMMoniuM salt)
- 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[biotinyl(polyethylene glycol)-2000] (aMMoniuM salt)
- 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[cyanur(polyethylene glycol)-2000] (aMMoniuM salt)
- Folic acid PEG DSPE
- 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[carboxy(polyethylene glycol)-2000] (aMMoniuM salt)