6-Nitroindoline Chemical Properties

Melting point:

67-69 °C (lit.)

Boiling point:

291.62°C (rough estimate)

Density 

1.2739 (rough estimate)

refractive index 

1.6000 (estimate)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

form 

Crystalline Powder or Crystals

pka

3.39±0.20(Predicted)

color 

Orange or red

BRN 

156434

CAS DataBase Reference

19727-83-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

RTECS 

NM1950000

Hazard Note 

Irritant

HS Code 

29339900

Toxicity

mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00607,

MSDS

• Language:English Provider:2,3-Dihydro-6-nitro-1H-indole
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

6-Nitroindoline Usage And Synthesis

Chemical Properties

orange crystalline powder or red crystals

Uses

• ;Reactant for preparation of 2-[(2,3-Dihydro-1H-indol-1-yl)methyl]melatonin analogs as novel MT2-selective melatonin receptor antagonists1• ;Reactant for synthesis of isoindigo and azaisoindigo glycosides as anticancer agents2• ;Reactant for preparation of arylfurancarboxamides with Nav1.8 voltage-gated Na channel blocking/analgesic activities3• ;Reactant for preparation of bicyclic benzamides as 5-HT1 receptor agonists4• ;Reactant for preparation of antiarrhythmic benzopyrans5• ;Reactant for preparation of 5-HT2C/2B receptor antagonists6

Uses

• Reactant for preparation of 2-[(2,3-Dihydro-1H-indol-1-yl)methyl]melatonin analogs as novel MT2-selective melatonin receptor antagonists
• Reactant for synthesis of isoindigo and azaisoindigo glycosides as anticancer agents
• Reactant for preparation of arylfurancarboxamides with Nav1.8 voltage-gated Na channel blocking/analgesic activities
• Reactant for preparation of bicyclic benzamides as 5-HT1 receptor agonists
• Reactant for preparation of antiarrhythmic benzopyrans
• Reactant for preparation of 5-HT2C/2B receptor antagonists

6-Nitroindoline(19727-83-4)Related Product Information

• Indole-3-butyric acid
• 6-Nitroindole
• Indoline
• Indole-3-acetic acid
• 2-Methylindoline
• 4-Nitroindole
• 5-Nitroindole
• Indole
• Indometacin
• 7-Nitroindole
• Isoindoline
• 2,6-DINITROPHENOL
• 1-METHYL-5-NITROINDOLINE
• 5-BROMO-7-NITROINDOLINE
• 3',3'-Dimethyl-6-nitro-spiro[2H-1-benzopyran-2,2'-indoline]-1'-ethanol
• 1-ACETYL-5-BROMO-7-NITROINDOLINE
• 5-NITROINDOLINE
• NITROGEN DIOXIDE