Isocarbophos Chemical Properties

Melting point:

45～49℃

Boiling point:

385.1±44.0 °C(Predicted)

Density 

1.275±0.06 g/cm3(Predicted)

Flash point:

4 °C

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

-1.34±0.70(Predicted)

color 

Off-White

BRN 

2946521

Stability:

Hygroscopic

Major Application

agriculture
environmental

InChI

1S/C11H16NO4PS/c1-8(2)15-11(13)9-6-4-5-7-10(9)16-17(12,18)14-3/h4-8H,1-3H3,(H2,12,18)

InChIKey

YFVOXLJXJBQDEF-UHFFFAOYSA-N

SMILES

COP(N)(=S)Oc1ccccc1C(=O)OC(C)C

CAS DataBase Reference

24353-61-5(CAS DataBase Reference)

EPA Substance Registry System

Isocarbophos (24353-61-5)

Safety Information

Hazard Codes 

F;Xn,Xn,F,T

Risk Statements 

11-38-48/20-63-65-67-25-21

Safety Statements 

36/37-62-45

RIDADR 

UN 1294

WGK Germany 

3

RTECS 

VO4395900

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 2 Oral
Acute Tox. 3 Dermal

Toxicity

bird - wild,LD50,oral,750ug/kg (0.75mg/kg),Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973.

Isocarbophos Usage And Synthesis

Description

Isocarbophos is a broad-spectrum organophosphorus insecticide used to control a variety of leaf-eating and soil insects on rice, fruit and other crops^1-3. It can control various kinds of pests such as aphids, spider mite, borers and leaf rollers. However, it is an insecticide without EU regulatory approval for use. It has a moderate level of water solubility. It has caused environmental pollution in many areas but little is known regarding its environmental fate^1-2. It is highly toxic to mammals and also has a high potential for bioaccumulation. It is an acetyl cholinesterase inhibitor and a neurotoxin¹.

References

1. http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/987.htm
2. Rong, L., et al. "Isolation of an isocarbophos-degrading strain of Arthrobacter sp. scl-2 and identification of the degradation pathway." Journal of Microbiology & Biotechnology 19.11(2009):1439.
3. http://www.chemchina.com.cn/slden/cpyfw/ppysb/jscg/webinfo/2012/06/1342611935451309.htm

Uses

Isocarbophos is an organophosphorus pesticide residue found in spicy foods and nuts.

Definition

ChEBI: Isocarbophos is an organothiophosphate insecticide, an organic phosphonate, a phosphonic ester, a member of salicylates and an isopropyl ester. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical and an avicide. It is functionally related to an isopropyl salicylate.

Isocarbophos(24353-61-5)Related Product Information

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• BUTYL OLEATE
• Diphenyldiethoxysilane
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• ISOPROPYL LAURATE
• Sodium thiosulfate
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