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Isocarbophos

Basic information Description References Safety Supplier Related

Isocarbophos Basic information

Product Name:
Isocarbophos
Synonyms:
  • Isopropyl 2-[(aminomethoxyphosphinothioyl)oxy]benzoate
  • ISOCARBOFOS
  • ISOCARBOPHOS
  • 2-((aminomethoxyphosphinothioyl)oxy)-benzoicaci1-methylethylester
  • ai3-27659
  • 2-((Amino(methoxy)phosphinothioyl)oxy)benzoic acid 1-methylethyl ester
  • Isocarbophos,O-Methyl O-[2-(isopropoxycarbonyl)phenyl] phosphoramidothioate
  • O-methyl-O-(2-carboisopropoxyphenyl) phosphoroamidothioate
CAS:
24353-61-5
MF:
C11H16NO4PS
MW:
289.29
EINECS:
246-192-1
Product Categories:
  • INSECTICIDE
Mol File:
24353-61-5.mol
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Isocarbophos Chemical Properties

Melting point:
45~49℃
Boiling point:
385.1±44.0 °C(Predicted)
Density 
1.275±0.06 g/cm3(Predicted)
Flash point:
4 °C
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-1.34±0.70(Predicted)
color 
Off-White
BRN 
2946521
Stability:
Hygroscopic
CAS DataBase Reference
24353-61-5(CAS DataBase Reference)
EPA Substance Registry System
Isocarbophos (24353-61-5)
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Safety Information

Hazard Codes 
F;Xn,Xn,F,T
Risk Statements 
11-38-48/20-63-65-67-25-21
Safety Statements 
36/37-62-45
RIDADR 
UN 1294
WGK Germany 
3
RTECS 
VO4395900
Toxicity
bird - wild,LD50,oral,750ug/kg (0.75mg/kg),Toxicology and Applied Pharmacology. Vol. 26, Pg. 154, 1973.
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Isocarbophos Usage And Synthesis

Description

Isocarbophos is a broad-spectrum organophosphorus insecticide used to control a variety of leaf-eating and soil insects on rice, fruit and other crops1-3. It can control various kinds of pests such as aphids, spider mite, borers and leaf rollers. However, it is an insecticide without EU regulatory approval for use. It has a moderate level of water solubility. It has caused environmental pollution in many areas but little is known regarding its environmental fate1-2. It is highly toxic to mammals and also has a high potential for bioaccumulation. It is an acetyl cholinesterase inhibitor and a neurotoxin1.

References

  1. http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/987.htm
  2. Rong, L., et al. "Isolation of an isocarbophos-degrading strain of Arthrobacter sp. scl-2 and identification of the degradation pathway." Journal of Microbiology & Biotechnology 19.11(2009):1439.
  3. http://www.chemchina.com.cn/slden/cpyfw/ppysb/jscg/webinfo/2012/06/1342611935451309.htm

Uses

Isocarbophos is an organophosphorus pesticide residue found in spicy foods and nuts.

Definition

ChEBI: Isocarbophos is an organothiophosphate insecticide, an organic phosphonate, a phosphonic ester, a member of salicylates and an isopropyl ester. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical and an avicide. It is functionally related to an isopropyl salicylate.

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