IRL-2500
IRL-2500 Basic information
- Product Name:
- IRL-2500
- Synonyms:
-
- IRL-2500
- N-3-[1,1'-BIPHENYL]-4-YL-N-(3,5-DIMETHYLBENZOYL)-N-METHYL-D-ALANYL-L-TRYPTOPHAN
- L-Tryptophan, 3-[1,1'-biphenyl]-4-yl-N-(3,5-dimethylbenzoyl)-N-methyl-D-alanyl-
- ((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
- ((R)-3-([1,1'-Biphenyl]-4-yl)-2-(N,3,5-trimethylbenzamido)propanoyl)-L-tryptophan
- CAS:
- 169545-27-1
- MF:
- C36H35N3O4
- MW:
- 573.68
- Product Categories:
-
- Endothelin receptor
- Mol File:
- 169545-27-1.mol
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IRL-2500 Chemical Properties
- Boiling point:
- 893.7±65.0 °C(Predicted)
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- Soluble to 100 mM in 1eq. NaOH
- form
- Powder
- pka
- 3.34±0.10(Predicted)
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IRL-2500 Usage And Synthesis
Uses
IRL 2500 is a potent endothelin ETB selective antagonist.
Biological Activity
Potent endothelin receptor antagonist; shows some selectivity for ET B receptors (IC 50 values are 1.3 and 94 nM for ET B and ET A receptors respectively). Inhibits ET B receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo .
storage
Desiccate at RT
IRL-2500Supplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
AdooQ BioScience, LLC
- Tel
- +1 (866) 930-6790
- info@adooq.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai Chaolan Chemical Technology Center
- Tel
- QQ:65489617 15618227136
- info@SuperLan-chem.com
Aikon International Limited
- Tel
- 025-66113011 18112977050
- sales01@aikonchem.com