2-Bromo-3-fluoropyridine Chemical Properties

Boiling point:

62°C

Density 

1.74

refractive index 

1.5450

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

clear liquid

pka

-1.63±0.10(Predicted)

color 

Colorless to Light yellow to Light orange

CAS DataBase Reference

40273-45-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

T,Xi,Xn

Risk Statements 

22-37/38-41

Safety Statements 

26-39

RIDADR 

1993

Hazard Note 

Toxic

HazardClass 

IRRITANT

HazardClass 

6.1

PackingGroup 

Ⅲ

HS Code 

29333990

2-Bromo-3-fluoropyridine Usage And Synthesis

Chemical Properties

Colorless to slightly yellow liquid

Uses

2-Bromo-3-fluoropyridine is a chemical intermediate that belongs to the group of heterocyclic compounds. It is synthesized by the reaction of sodium methanethiolate and formaldehyde with magnesium. The product yield is not very high, but 2-bromo-3-fluoropyridine can be used for the synthesis of other heterocyclic compounds. The compound was first isolated in 1887 by J. Grignard from a reaction between bromine and formaldehyde. It has been shown to have formylation, nucleophilic substitution, and condensation reactions as its transition states. 2-Bromo-3-fluoropyridine can be prepared from the Grignard reagent, methanethiolate, and chlorine or magnesium chloride in an ether solution at room temperature. This compound has also been used as a reagent for the preparation of difluoromethoxybenz.

2-Bromo-3-fluoropyridine(40273-45-8)Related Product Information

• Flupirtine
• 2-Bromopyridine
• 3-Fluoropyridine
• 2-Fluoropyridine
• Ethyl bromodifluoroacetate
• 2-Chloro-3-cyanopyridine
• 1-Hexadecylpyridinium bromide
• 3-Hydroxypyridine
• 3-Aminopyridine
• 2-Bromo-3,5-dichloropyridine
• 2-Bromo-4-fluoropyridine
• 2-Bromo-4-chloropyridine
• 2-Bromo-4-methylpyridine
• 2-Bromo-3-methylbenzaldehyde
• 2-Bromo-4-nitroimidazole
• 2-Bromo-5,6-diphenylpyrazine
• 2-Bromo-3-trifluoromethylpyridine
• 3-Amino-2-bromopyridine