DBCO-sulfo-NHS ester Chemical Properties

Melting point:

240-260 °C

storage temp. 

-20°C

form 

Solid

color 

Off-white to yellow

InChIKey

NSZPURPXEZOXPC-UHFFFAOYSA-N

SMILES

C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCCCC(=O)ON1C(CC(S(O)(=O)=O)C1=O)=O.[NaH]

Safety Information

WGK Germany 

3

DBCO-sulfo-NHS ester Usage And Synthesis

Description

DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system.

reaction suitability

reaction type: click chemistry
reagent type: linker

IC 50

Cleavable Linker

DBCO-sulfo-NHS ester(1400191-52-7)Related Product Information

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