Basic information Safety Supplier Related

DBCO-sulfo-NHS ester

Basic information Safety Supplier Related

DBCO-sulfo-NHS ester Basic information

Product Name:
DBCO-sulfo-NHS ester
Synonyms:
  • DBCO-sulfo-NHS ester
  • DBCO-sulfo-SE
  • Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester
  • DBCO-sulfo-NHS ester,DBCO-sulfo-SE
  • DBCO-Sulfo-NHS ester sodium
  • DBCO-C6-Sulfo-NHS ester
CAS:
1400191-52-7
MF:
C25H23N2NaO8S
MW:
534.51
Mol File:
1400191-52-7.mol
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DBCO-sulfo-NHS ester Chemical Properties

Melting point:
240-260 °C
storage temp. 
-20°C
InChIKey
NSZPURPXEZOXPC-UHFFFAOYSA-N
SMILES
C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCCCC(=O)ON1C(CC(S(O)(=O)=O)C1=O)=O.[NaH]
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Safety Information

WGK Germany 
3
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DBCO-sulfo-NHS ester Usage And Synthesis

Description

DBCO-Sulfo-NHS ester is a water-soluble sulfocated reagent containing DBCO moiety. It can be used for simple and efficient labeling of antibodies, proteins and any other primary amine-bearing macromolecules with DBCO moiety in 100% aqueous buffers. DBCO is commonly used for copper-free Click Chemistry reactions.

Uses

Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system.

DBCO-sulfo-NHS esterSupplier

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