LENAMPICILLIN
LENAMPICILLIN Basic information
- Product Name:
- LENAMPICILLIN
- Synonyms:
-
- LENAMPICILLIN
- 1,3-Dioxole, 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid deriv.
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, [2S-[2a,5a,6b(S*)]]-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, (2S,5R,6R)- (9CI)
- Antibiotic KBT 1585
- Lenanpicillin
- Varacllin
- (2S,5β,6R)-6α-[[(R)-Amino(phenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
- CAS:
- 86273-18-9
- MF:
- C21H23N3O7S
- MW:
- 461.49
- EINECS:
- 200-258-5
- Mol File:
- 86273-18-9.mol
LENAMPICILLIN Chemical Properties
- storage temp.
- 2-8°C
LENAMPICILLIN Usage And Synthesis
Description
Lenampicillin hydrochloride is improved bioavailability.
Chemical Properties
Lenampicillin Hydrochloride (Lenampicillin Hydrochloride): C21H23N3O7S?HCl, [80734-02-7]. White to yellowish-white powder with a strange odor and bitter taste. Very soluble in water, soluble in methanol or ethanol, insoluble in ether. Melting point 145°C (decomposition). Acute toxicity LD 50 male and female rats, male and female mice (mg/kg): about 10,000, about 10,000, 8294, 8492 orally; 4362, 4471, 3576, 4284 subcutaneous injection; 876, 838, 711, 775 intravenous injection. Acute toxicity LD50 dog (mg/kg): >300 oral.
Originator
Kanebo (Japan)
Definition
ChEBI: Lenampicillin is a penicillanic acid ester that is the (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester of ampicillin. It is a prodrug of ampicillin. It has a role as a prodrug. It is a penicillanic acid ester and a ketene acetal. It is functionally related to an ampicillin.
brand name
Varacillin; Takacillin
LENAMPICILLIN Preparation Products And Raw materials
Raw materials
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