Sofosbuvir D6 Usage And Synthesis

Uses

It is the isotope labelled analog of Sofosbuvir. Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2?-deoxy-2?-α-fluoro-β-C-methyluridine-5?-monophosphate and is currently being investigated in phase

Uses

Isotope labelled PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir D6(1868135-06-1)Related Product Information

• Sofosbuvir Impurity 8
• PSI 352707-13C,D3
• PSI-7976
• PSI-7977-13C-d3
• ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
• Sofosbuvir IMpurity B
• Sofosbuvir IMpurity C 1337482-15-1
• L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester
• ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
• 2'-deoxy-2'-fluoro-2'-C-methyluridine
• PSI-6130 derivative
• Sofosbuvir IMpurity
• 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
• Sofosbuvir Impurity
• Sofosbuvir metabolites GS566500
• Sofosbuvir metabolites
• Sofosbuvir Impurity 19
• PSI-6206 13CD3