Mes-PEG5- THP
Mes-PEG5- THP Basic information
- Product Name:
- Mes-PEG5- THP
- Synonyms:
-
- Mes-PEG5- THP
- Mes-PEG4- THP
- MS-PEG4-THP
- CAS_145927-73-7
- Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-, 1-methanesulfonate
- MSPEG4THP,MS-PEG-4-THP,PROTAC Linkers,inhibit,MS PEG4 THP,Inhibitor
- 2-(2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl methanesulfonate
- CAS:
- 145927-73-7
- MF:
- C14H28O8S
- MW:
- 356.43
- Mol File:
- 145927-73-7.mol
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Mes-PEG5- THP Chemical Properties
- form
- Liquid
- color
- Light yellow to light brown
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Mes-PEG5- THP Usage And Synthesis
Biological Activity
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Mes-PEG5- THPSupplier
Borenpharm Co., Ltd
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- 027-65563561
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Shanghai EFE Biological Technology Co., Ltd.
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- 021-65675885 18964387627
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Zhengzhou Acme Chemical Co., Ltd.
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- 0371-0371-55629727 13323845623
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Amatek Scientific Co. Ltd.
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- 0512-56316828
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TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com