Azido-PEG1-CH2CO2H Chemical Properties

solubility 

Soluble in Water, DCM

Azido-PEG1-CH2CO2H Usage And Synthesis

Description

Azido-PEG1-CH2CO2H is a PEG linker containing an azide group with a terminal carboxylic acid. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

2-(2-Azidoethoxy)acetic Acid is an intermediate in the synthesis of 3-O-Desethyl-5-O-desmethyl Amlodipine (D291305). 3-O-Desethyl-5-O-desmethyl Amlodipine is an impurity of Amlodipine (A633495), which is a dihydropyridine calcium channel blocker.

Azido-PEG1-CH2CO2H(79598-48-4)Related Product Information

• 4,4-Piperidinediol hydrochloride
• Isonipecotic acid
• 4-Pyrimidinecarboxylic acid
• Benzyl 4-hydroxy-1-piperidinecarboxylate
• Hexahydroisonicotinamide
• 4-HYDROXY-3-METHYLBENZOIC ACID