Tos-PEG3-CH2CO2H Chemical Properties

Boiling point:

512.8±40.0 °C(Predicted)

Density 

1.306±0.06 g/cm3(Predicted)

pka

3.39±0.10(Predicted)

Tos-PEG3-CH2CO2H Usage And Synthesis

Description

Tos-PEG3-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Tos-PEG3-CH2CO2H(1807537-35-4)Related Product Information

• Tos-PEG4-acid
• Tos-PEG5 t-butyl ester
• Tos-PEG2-CH2CO2tBu
• Tos-PEG2-t-butyl ester
• Tos-PEG4-CH2CO2H
• Tos-PEG4-t-butyl ester
• Tos-PEG6-t-Butyl ester
• Tos-PEG3-CH2CO2tBu
• Tos-PEG5-CH2CO2H
• Tos-PEG5-CH2CO2t-butyl ester