Moroxydine hydrochloride Chemical Properties

Melting point:

211-214 °C(lit.)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMSO (Very Slightly, Heated), Water (Slightly)

form 

Solid

color 

Off-White

Merck 

14,6272

InChIKey

FXYZDFSNBBOHTA-UHFFFAOYSA-N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

RTECS 

QD9815000

HS Code 

2934.99.4700

MSDS

• Language:English Provider:SigmaAldrich

Moroxydine hydrochloride Usage And Synthesis

Originator

Grippe,Nissin

Uses

Moroxydine is an antiviral used against a number of RNA and DNA viruses.

Uses

Moroxydine hydrochloride is an antiviral used against a number of RNA and DNA viruses.

Manufacturing Process

43.5 g morpholine, 41.7 ml concentrated hydrochloric acid, 40 ml of water, and 42 g dicyandiamide are refluxed for 48 hours, whereupon the reaction mixture is cooled to +5°C and filtered. The filtrate is evaporated to dryness and extracted and extracted with boiling ethanol. Yield: 50 g. The formed 4- morpholinecarboximidoylguanidine hydrochloride is purified by recrystallization from methanol. The salt may be converted into the base by adding equivalent of any basic compound (triethylamine, sodium bicarbonate and so on).
In practice it is usually used as hydrochloride.

Therapeutic Function

Antiviral

General Description

Determination of moroxydine hydrochloride in Gan Mao Qing capsules by derivative spectrophotometric signal multiplier method has been reported. Therapeutical efficiency of moroxidine hydrochloride against herpes virus induced keratoconjunctivitis has been evaluated by immunofluorescence techniques.

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