ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Proline derivatives > 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Basic information
- Product Name:
- 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
- Synonyms:
-
- N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID
- N-BOC-TRANS-4-FLUORO-L-PROLINE
- N-T-BOC-TRANS-4-FLUORO-L-PROLINE
- N-(TERT-BUTOXYCARBONYL)-(2S,4R)-4-FLUOROPROLINE
- BOC-TRANS-4-FLUORO-L-PROLINE
- (2S,4R)-N-Boc-trans-4-Fluoro-L-Proline
- (2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N4-BOC protected
- trans-4-Fluoro-L-proline, N-BOC protected
- CAS:
- 203866-14-2
- MF:
- C10H16FNO4
- MW:
- 233.24
- Product Categories:
-
- Carboxylic Acids (Chiral)
- Chiral Building Blocks
- Synthetic Organic Chemistry
- Chiral Building Blocks
- Heterocyclic Building Blocks
- Pyrrolidines
- Mol File:
- 203866-14-2.mol
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1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Chemical Properties
- Melting point:
- 115-119°C
- Boiling point:
- 346.0±42.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- refractive index
- -69 ° (C=1, MeOH)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 3.53±0.40(Predicted)
- color
- White to Almost white
- optical activity
- [α]22/D -65.0±5°, c = 1 in chloroform
- InChIKey
- YGWZXQOYEBWUTH-RQJHMYQMSA-N
- CAS DataBase Reference
- 203866-14-2(CAS DataBase Reference)
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1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate Usage And Synthesis
Chemical Properties
White powder
Uses
N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.
1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylateSupplier
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1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate(203866-14-2)Related Product Information
- Nr
- (2R,4S)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid
- (2R,4R)-1-[(tert-butoxy)carbonyl]-4-fluoropyrrolidine-2-carboxylic acid
- N-BOC-cis-4-fluoro-L-proline
- Cbz-D-Valine
- L-Proline
- D-Proline
- N-Boc-cis-4-Fluoro-D-Proline
- BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER
- BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER,N-T-BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER,N-Boc-trans-4-fluoro-L-proline methyl ester
- N-BOC-4,4-difluoro-L-proline
- BOC-TRANS-4-FLUORO-5-OXO-L-PROLINE METHYL ESTER
- 1-(1,1-Dimethylethyl) (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate